Webfind local businesses, view maps and get driving directions in google maps. Avoid traffic with optimized routes. Learn more about our mobile apps. Step by step directions for your drive or walk. Webthe total driving distance from san francisco, ca to san diego, ca is 501 miles or 806 kilometers. Your trip begins in san francisco, california. It ends in san diego, california. Webget directions, maps, and traffic for san diego, ca. Check flight prices and hotel availability for your visit. Webhere's a sample itinerary for a drive from fresno…

Webcheck current highway conditions. This highway information is the latest. No traffic restrictions are reported for this area. Data provided by caltrans. Not for emergency use. In an emergency visit official caltrans website. View on google maps. It runs from the southern edge of mission bay at sunset cliffs boulevard in san diego, california ,. Google maps says 18 minute delayed due to a “road closure” but we’ve been here.